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Three Indian Scientists Win Tata Transformation Prize

Three Indian Scientists Win Tata Transformation Prize

India-West Staff Reporter

NEW YORK, NY – Tata Sons and The New York Academy of Sciences announced the first winners of the Tata Transformation Prize that recognizes and supports scientists in India who are developing solutions to important societal challenges.

The prize was established in 2022 by the two organizations.

Three scientists were selected from 169 entries by an international jury of renowned experts for their innovations in food security, sustainability, and healthcare. Each winner will receive Rs 20 million ($240,000) and will be honored at a ceremony in Mumbai in December 2023, a press release said.

The winners are:

Food Security: Shilpi Sharma, PhD, Indian Institute of Technology Delhi

was selected by the jury for her work in the engineering of the soil microbiome using synthetic microbial communities.

Plant diseases threaten crop productivity and, consequently, the global economy. Unlike conventional farming that uses agrochemicals and synthetic fertilizers, soil amended organically has the natural ability to suppress a wide range of plant pathogens.

Starting from naturally suppressive soil, Shilpi will catalog the active microbial players and their mechanism of suppression of a range of phytopathogens.

Her work will be the first to map the natural suppressive potential of soil across six states of India and to harness this potential by microbiome engineering to facilitate sustainable agriculture in the country and beyond.

Sustainability: Purnananda Guptasarma, PhD, Indian Institute of Science Education and Research, Mohali was selected by the jury for his breakthrough methods to degrade polyethylene terephthalate a common plastic pollutant, using enzymes.

PET is currently produced and used at unsustainable levels, creating worldwide plastic pollution and micro-plastic contamination in the air, water, and soil, as well as in animal and human bodies.

Only 9% of PET is recycled worldwide. Guptasarma’s enzyme-driven strategy uses engineered thermostable enzymes and reactions to demonstrate that solid PET can be broken up into its smallest molecular building blocks with high yield and ultra-high purity to enable PET’s degradation and recycling into virgin plastic.

Building on this proof of concept at the laboratory-scale, Guptasarma will further identify and improve enzymatic reagents and reactions for PET degradation and attempt to produce the best enzymes in quantities allowing pilot-scale PET-waste degradation and recycling.

Healthcare: Anurag Singh Rathore, PhD, Indian Institute of Technology Delhi is a healthcare pioneer aiming to reduce the manufacturing cost of biotherapeutics for treating cancer and autoimmune diseases, thus enabling equal access to these top-tier, expensive treatments currently out of reach for 90% of the Indian population.

Rathore has established a state-of-the-art drug manufacturing facility with continuous processing that incorporates novel methods for real-time process monitoring and control.

Rathore’s innovation is projected to reduce manufacturing costs by 50-75%, making best-in-class biotherapeutics for complex diseases significantly more affordable for Indian populations in need and further advancing India’s position at the forefront of global medical innovation.

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